List ofpuBRcations
نویسندگان
چکیده
A series of p-ammo carbonyl compounds containing coumann (4a-h) and benzofuran (6a-i) moieties was synthesized by a three component Mannich reaction of 3-acetyl-2//-chromen-2-one (1) or l-(l-benzofuran-2-yl) ethanone (5) with p-substjiuied aromatic aldehydes (2ag) and aromatic amines (3a-b) in the presence of cerric ammonium nitrate as a catalyst The newly synthesized compounds were screened for antimicrobial and antioxidant activities Compounds 4b, 4e, 4f, 6f, 6g, and 6i showed microbial inhibition with minimal inhibition concentration ranging between 0 040 and 0 500 mg/mL, compounds 4b, 4c, 6e, 6e, and 6i showed promising free radical scavenging activity and compounds 4b, 4f, 6c, 6d, and 6h showed good chelating ability with Fê "*" ions The synthesized compounds were studied for docking on the enzyme, glucosamine-6-phosphate synthase to predict the binding atfinity and orientation at the active site of the receptor. R Kenchappa Y D Bodke (EI) V K Bhovi Deparlmeni of P G Studies and Research in Industrial Chemistry, Jnana Sahyadn, Kuvempu University Shankaraghatta, Shivamogga 577451, Karnataka, India e-mail yd_bodke@yahoo co in, ydbodke@gmail com S K Peethambar Department of P G Studies and Research in Biochemistry, Jnana Sahyadn, Kuvempu University, Shankaraghatta, Shivamogga 577451, Karnataka, India S Telkar Department of P G Studies and Research in Biotechnology, Jnana Sahyadn, Kuvempu University, Shankaraghatta, Shivamogga 577451, Karnataka, India
منابع مشابه
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Thisstudy sought to evaluate the learners' achievements with the visual learning style when exposed to the sentence making and word list approaches. On that account, 45 basic level participants who studied at the Iran Language Institute (ILI), Bushehr, took part in this research study. At the outset, the learners were given Barsch learning style inventory (1991) to determine the learners' learn...
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